Pest Management Science (2007) 63, 935-940
Jun Young Cho, Gyung Ja Choi, Seung Wan Son, Kyoung Soo Jang, He Kyoung Lim, Sun Og Lee, Nack Do Sung, Kwang Yun Cho and Jin-Cheol Kim (2007)
Isolation and antifungal activity of lignans from Myristica fragrans against various plant pathogenic fungi
Pest Management Science 63 (9), 935-940
Abstract: BACKGROUND: In a search for plant extracts with potent in vivo antifungal activity against various plant diseases, we found that treatment with a methanol extract of Myristica fragrans Houttyn (nutmeg) seeds reduced the development of various plant diseases. The objectives of the present study were to isolate and determine antifungal substances from My. fragrans and to evaluate their antifungal activities.
RESULTS: Three antifungal lignans were isolated from the methanol extract of My. fragrans seeds and identified as erythro-austrobailignan-6 (EA6), meso-dihydroguaiaretic acid (MDA) and nectandrin-B (NB). In vitro antimicrobial activity of the three lignans varied according to compound and target species. Alternaria alternata, Colletotrichum coccodes, C. gloeosporioides, Magnaporthe grisea, Agrobacterium tumefaciens, Acidovorax konjaci and Burkholderia glumae were relatively sensitive to the three lignans. In vivo, all three compounds effectively suppressed the development of rice blast and wheat leaf rust. In addition, EA6 and NB were highly active against the development of barley powdery mildew and tomato late blight, respectively. Both MDA and NB also moderately inhibited the development of rice sheath blight.
CONCLUSION: This is the first study to demonstrate the in vitro and in vivo antifungal activities of the three lignans from My. fragrans against plant pathogenic fungi.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Jin-Cheol Kim
Research topic(s) for pests/diseases/weeds:
control - general
Pest and/or beneficial records:
| Beneficial | Pest/Disease/Weed | Crop/Product | Country | Quarant.
|
|---|---|---|---|---|
| Phytophthora infestans | ||||
| Blumeria graminis | ||||
| Alternaria alternata | ||||
| Colletotrichum gloeosporioides | ||||
| Colletotrichum coccodes | ||||
| Agrobacterium tumefaciens | ||||
| Pyricularia oryzae | ||||
| Burkholderia glumae | ||||
| Acidovorax konjaci |
