PLoS ONE (2016) 11 (4 - e0154058)

Zhitian Zheng, Xiumei Liu, Bin Li, Yiqiang Cai, Yuanye Zhu and Mingguo Zhou (2016)
Myosins FaMyo2B and Famyo2 affect asexual and sexual development, reduces pathogenicity, and FaMyo2B acts jointly with the myosin passenger protein FaSmy1 to affect resistance to phenamacril in Fusarium asiaticum
PLoS ONE 11 (4 - e0154058)
Abstract: We previously reported that mutations occurred in the gene myosin5 were responsible for resistance to the fungicide phenamacril in Fusarium graminearum. Here, we determined whether there is a functional link between phenamacril resistance and the myosin proteins FaMyo2B and Famyo2 in Fusarium asiaticum, which is the major causal agent of Fusarium head blight in China. We found that FaMyo2B acts jointly with FaSmy1 to affect resistance to phenamacril in F. asiaticum. We also found that FaMyo2B disruption mutant and Famyo2 deletion mutant were defective in hyphal branching, conidiation, and sexual reproduction. ΔFamyo2 also had an enhanced sensitivity to cell wall damaging agents and an abnormal distribution of septa and nuclei. In addition, the FaMyo2B and Famyo2 mutants had reduced pathogenicity on wheat coleoptiles and flowering wheat heads. Taken together, these results reveal that FaMyo2B and Famyo2 are required for several F. asiaticum developmental processes and activities, which help us better understand the resistance mechanism and find the most effective approach to control FHB.
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Database assignments for author(s): Ming-Guo Zhou

Research topic(s) for pests/diseases/weeds:
pesticide resistance of pest

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Fusarium asiaticum