PLoS ONE (2012) 7 (8 - e42857)

Ruth Kigozi, Sanjiv M. Baxi, Anne Gasasira, Asadu Sserwanga, Stella Kakeeto, Sussann Nasr, Denis Rubahika, Gunawardena Dissanayake, Moses R. Kamya, Scott Filler and Grant Dorsey (2012)
Indoor residual spraying of insecticide and malaria morbidity in a high transmission intensity area of Uganda
PLoS ONE 7 (8 - e42857)
Abstract:
Background
Recently the use of indoor residual spraying of insecticide (IRS) has greatly increased in Africa; however, limited data exist on the quantitative impacts of IRS on health outcomes in highly malaria endemic areas.
Methodology/Principal Findings
Routine data were collected on more than 90,000 patient visits at a single health facility over a 56 month period covering five rounds of IRS using three different insecticides. Temporal associations between the timing of IRS and the probability of a patient referred for microscopy having laboratory confirmed malaria were estimated controlling for seasonality and age. Considering patients less than five years of age there was a modest decrease in the odds of malaria following the 1^st round of IRS using DDT (OR = 0.76, p<0.001) and the 2^nd round using alpha-cypermethrin (OR = 0.83, p = 0.002). Following rounds 3–5 using bendiocarb there was a much greater decrease in the odds of malaria (ORs 0.34, 0.16, 0.17 respectively, p<0.001 for all comparisons). Overall, the impact of IRS was less pronounced among patients 5 years or older.
Conclusions/Significance
IRS was associated with a reduction in malaria morbidity in an area of high transmission intensity in Uganda and the benefits appeared to be greatest after switching to a carbamate class of insecticide.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Full text of article

Research topic(s) for pests/diseases/weeds:
control - general

---

Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Anopheles gambiae		Uganda