Nematology (2002) 4, 55-63

James K. Nitao, Susan L.F. Meyer, James E. Oliver, Walter F. Schmidt and David J. Chitwood (2002)
Isolation of flavipin, a fungus compound antagonistic to plant-parasitic nematodes
Nematology 4 (1), 55-63
Abstract: An isolate of the fungus Chaetomium globosum produced culture broths that inhibited in vitro egg hatch and juvenile mobility of root-knot nematode (Meloidogyne incognita) and hatch of soybean cyst nematode (Heterodera glycines). Extraction and bioassay-directed fractionation of the culture broth filtrate determined that flavipin, a low molecular weight compound, was the fungus metabolite responsible for most of the nematode-antagonistic activity. Synthesis of flavipin permitted evaluation of the compound as a suppressor of nematode populations on plants in glasshouse studies. Muskmelon (Cucumis melo) plants in steamed and unsteamed soil were inoculated with root-knot nematodes and various concentrations of flavipin were applied to the soil. Contrary to expectations from the in vitro studies, the number of galls per g of roots increased with flavipin treatment at the 14-day harvest. No effect of flavipin on nematode populations was found at the 55-day harvest. In general, plant growth and nematode populations were greater in plants grown in steamed soil.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): David J. Chitwood, Susan L. F. Meyer

Research topic(s) for pests/diseases/weeds:
control - general
biocontrol - natural enemies
Research topic(s) for beneficials or antagonists:
general biology - morphology - evolution
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Meloidogyne incognita	Melon (Cucumis melo)
	Heterodera glycines
Chaetomium globosum (antagonist)