Molecular Plant-Microbe Interactions (2001) 14, 925-928

M. Paula Filippone, Juan C. Diaz-Ricci, Atilio P. Castagnaro and Ricardo N. Farías (2001)
Effect of fragarin on the cytoplasmic membrane of the phytopathogen Clavibacter michiganensis
Molecular Plant-Microbe Interactions 14 (7), 925-928
Abstract: Fragarin, an antibiotic that was isolated and purified from a soluble fraction of strawberry leaves, may be a new type of preformed antimicrobial compound (phytoanticipin). Here, we report that the growth and oxygen consumption of the phytopathogenic bacterium Clavibacter michiganensis were rapidly inhibited after the addition of fragarin to cultures. Also, dissipation of the membrane potential and an increase of cell membrane permeability were observed in the presence of fragarin. The ability of fragarin to dissipate the membrane potential was confirmed with the use of small unilamellar liposomes made with lipids extracted from C. michiganensis. Our results suggest that fragarin is able to act at the membrane level, and that this action is correlated with a decrease in cell viability.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Atilio Pedro Castagnaro

Research topic(s) for pests/diseases/weeds:
control - general

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Clavibacter michiganensis