Journal of the American Mosquito Control Association (2004) 20, 438-443

Julien Bonnet, Vincent Corbel, Frederic Darriet, Fabrice Chandre and Jean-Marc Hougard (2004)
Topical applications of pyrethroid and organophosphate mixtures revealed positive interactions against pyrethroid-resistant Anopheles gambiae
Journal of the American Mosquito Control Association 20 (4), 438-443
Abstract: The efficacy of a binary mixture of bifenthrin (pyrethroid) and chlorpyrifos-methyl (organophosphate) has been tested against susceptible and pyrethroid-resistant strains of Anopheles gambiae Giles, the major malaria vector in sub-Saharan Africa. Dose-mortality regression lines were determined for each insecticide alone and in mixtures by topical applications on adult female mosquitoes. A combination index (CI) was used to quantify the interactions occurring between the pyrethroid and organophosphate insecticides. The results revealed synergism at high doses against both susceptible (0.7 > CI > 0.3) and pyrethroid-resistant (0.9 > CI > 0.7) An. gambiae. These results suggest that insecticide mixtures may be an alternative strategy for vector control, especially in areas where mosquitoes are resistant to pyrethroids.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Database assignments for author(s): Vincent Corbel, Fabrice Chandre, Frederic Darriet, Jean-Marc Hougard

Research topic(s) for pests/diseases/weeds:
control - general
pesticide resistance of pest

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Anopheles gambiae		Benin