Journal of Medical Entomology (2020) 57, 1168-1175

Koffi Mensah Ahadji-Dabla, Daniel Romero-Alvarez, Innocent Djègbè, Adjovi Djifa Amoudji, Georges Yawo Apétogbo, Rousseau Djouaka, Komlanvi Oboussoumi, Agnidoufèyi Aawi, Tinah Atcha-Oubou, A. Townsend Peterson and Guillaume Koffivi Ketoh (2020)
Potential roles of environmental and socio-economic factors in the distribution of insecticide resistance in Anopheles gambiae sensu lato (Culicidae: Diptera) across Togo, West Africa
Journal of Medical Entomology 57 (4), 1168-1175
Abstract: Vector control strategies recommended by the World Health Organization are threatened by resistance of Anopheles mosquitoes to insecticides. Information on the distribution of resistant genotypes of malaria vectors is increasingly needed to address the problem. Ten years of published and unpublished data on malaria vector susceptibility/resistance and resistance genes have been collected across Togo. Relationships between the spatial distribution of resistance status and environmental, socio-economic, and landscape features were tested using randomization tests, and calculating Spearman rank and Pearson correlation coefficients between mosquito mortality and different gridded values. Anopheles gambiae sensu lato was resistant to DDT, pyrethroids, and the majority of carbamates and organophosphates. Three sibling species were found (i.e., An. gambiae, Anopheles coluzzii, and Anopheles arabiensis) with four resistance genes, including kdr (L1014F, L1014S, and N1575Y) and ace1 (G119S). The most frequent resistance gene was L1014F. Overall, no association was found between the susceptibility/resistance status and environmental features, suggesting that evolution of resistance may be most closely related to extreme selection from local insecticide use. Nevertheless, further research is necessary for firm conclusions about this lack of association, and the potential role of landscape characteristics such as presence of crops and percentage of tree cover.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Andrew Townsend Peterson, Guillaume Koffivi Ketoh, Koffi Mensah Ahadji-Dabla

Research topic(s) for pests/diseases/weeds:
pesticide resistance of pest

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Anopheles gambiae		Togo
	Anopheles arabiensis		Togo
	Anopheles coluzzii		Togo