Journal of Entomological Science (2007) 42, 296-305

Feng-Ju Chen, Chang-Zhong Zhang and Xi-Wu Gao (2007)
In vitro inhibition of glutathione S-transferases by several insecticides and allelochemicals in cotton bollworm, Helicoverpa armigera Hübner
Journal of Entomological Science 42 (2), 296-305
Abstract: Glutathione S-transferases are a group of enzymes catalyzing the conjugation of reduced glutathione (GSH) with a wide range of xenobiotics bearing electrophilic sites. In insects, GSTs are involved in resistance to insecticides and allelochemicals. In vitro inhibitory effects of several insecticides and allelochemicals on glutathione S-transferases activity in the cotton bollworm, Helicoverpa armigera Hübner, were studied. All organophosphate, carbamate and pyrethroid insecticides tested demonstrated moderate or low inhibiting GST activity toward 1-chlorine-2, 4-ditrobenzo (CDNB). Three allelochemicals (quercetin, tannic acid and rutin) were the most potent inhibitors of the enzymes among all compounds tested. Tannic acid was competitive with CDNB, quercetin was noncompetitive, and rutin was neither competitive nor non-competitive.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Database assignments for author(s): Xi-Wu Gao

Research topic(s) for pests/diseases/weeds:
control - general
pesticide resistance of pest

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Helicoverpa armigera