Annual Review of Entomology (2002) 47, 501-533

Juan Ferré and Jeroen Van Rie (2002)
Biochemistry and genetics of insect resistance to Bacillus thuringiensis
Annual Review of Entomology 47, 501-533
Abstract: Bacillus thuringiensis (Bt) is a valuable source of insecticidal proteins for use in conventional sprayable formulations and in transgenic crops, and it is the most promising alternative to synthetic insecticides. However, evolution of resistance in insect populations is a serious threat to this technology. So far, only one insect species has evolved significant levels of resistance in the field, but laboratory selection experiments have shown the high potential of other species to evolve resistance against Bt. We have reviewed the current knowledge on the biochemical mechanisms and genetics of resistance to Bt products and insecticidal crystal proteins. The understanding of the biochemical and genetic basis of resistance to Bt can help design appropriate management tactics to delay or reduce the evolution of resistance in insect populations.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Juan Ferre, Jeroen Van Rie

Research topic(s) for pests/diseases/weeds:
biocontrol - natural enemies
pesticide resistance of pest
Research topic(s) for beneficials or antagonists:
resistance/tolerance/defence of host
review

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
Bacillus thuringiensis genes in crops (entomopathogen)