American Journal of Plant Sciences (2019) 10, 622-630

Naitong Yu, ianhua Wang, Naixin Yu, Xiaobao Zheng, Qin Zhou and Zhixin Liu (2019)
Bioinformatics analysis of the interaction between coat protein and nuclear shuttle protein in Babuvirus
American Journal of Plant Sciences 10 (4), 622-630
Abstract: Protein and protein interactions play important roles in many biological processes and are responsible for carrying out the function of biological regulatory network in living organisms. Previous study indicated that Banana bunchy top virus (BBTV) coat protein (CP) interacted with BBTV nuclear shuttle protein (NSP). However, the protein and protein interaction and the binding affinity of CP and NSP in Babuvirus are remaining unclear. In this study, the CPs and NSPs proteins of BBTV, Abaca bunchy top virus (ABTV) and Cardamom bushy dwarf virus (CBDV) were used for bioinformatic analysis. The binding free energy and the dissociation constant of the possible interaction proteins were tested in PPA-Pred2, and the results confirmed CP interaction with NSP in Babuvirus. The study will help us to understand the interaction between viral protein and viral protein, and the pathogenesis mechanism of Babuvirus in host plants.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)

Research topic(s) for pests/diseases/weeds:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Banana bunchy top virus	Banana/plantain (Musa)	China (south)
	Cardamom bushy dwarf virus
	Abaca bunchy top virus