Acta Entomologica Sinica (2004) 47, 429-433

Jie Li, Yu-Zhe Du, Fan Tong, Bing-Jun He and An-Xi Liu (2004)
Modulations by cAMP and cGMP of the high-voltage activated Ca²⁺ channels in the central neurons of the cotton bollworm, Helicoverpa armigera
Acta Entomologica Sinica 47 (4), 429-433
Abstract: The effects of cAMP and cGMP on the high-voltage activated (HVA) Ca²⁺ channels in the central neurons isolated from the 3rd instar larvae of the cotton, bollworm (Helicoverpa armigera) were studied using the whole-cell patch clamp technique. With barium as current carrier, the currents of Ca²⁺ channels were recorded by blocking Na⁺ and K⁺ currents. Extracellular application of 0.1 mmol/L forskolin, a stimulator of adenylyl cyclase (AC), had no effect on the peak amplitude of Ba²⁺ currents. In contrast, 1 mmol/L cGMP in the intracellular solution suppressed the current amplitude significantly and the inhibition was time- and dose-dependent. The results suggest that the activities of HVA Ca²⁺ channels in the cotton bollworm may not be affected by the elevated cAMP, but can be inhibited by the increased cGMP.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Database assignments for author(s): Bing-Jun He

Research topic(s) for pests/diseases/weeds:
molecular biology - genes
general biology - morphology - evolution

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Helicoverpa armigera