Acta Entomologica Sinica (2000) 43, 138-142

Yi-Dong Wu, Yi-Hua Yang, Jin Chen, Ai-Mei Li, Jin-Liang Shen and Wen-Biao Shen (2000)
Inhibition of cytochrome P450 in Helicoverpa armigera (Hübner) by piperonyl butoxide (PBO) and its synergism to pyrethroids
Acta Entomologica Sinica 43 (2), 138-142
Abstract: Treatment in vivo with PBO caused apparent reduction of the cytochrome P450 level in third instar larva of Helicoverpa armigera. At 1 hour after PBO treatment, the content of cytochrome P450 was only 43. 9 % of that in the control. At 12 hours after PBO treatment, the content of cytochrome P450 decreased to 23.4 % of the control. While 18 and 24 hours after treatment, the content of cytochrome P450 was 85.8 % and 70.0 % of the control respectively. The bioassay results indicated that PBO synergised 7 pyrethroids significantly, with the highest synergistic ratio (119.3) for fenvalerate and the lowest (2.1) for permethrin. Because the cytochrome P450 is an important detoxifying enzyme, the reduction of the cytochrome P450 level can impede the oxidative metabolism and cause obvious synergism to pyrethroids in H. armigera.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
(original language: Chinese)
Database assignments for author(s): Yihua Yang, Jin Liang Shen

Research topic(s) for pests/diseases/weeds:
pesticide resistance of pest
control - general

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Helicoverpa armigera