The Journal of Eukaryotic Microbiology (1999) 46, 464-468

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Thomas Trammer, Gabriela Chioralia, Walter A. Maier and Hanns M. Seitz (1999)
In vitro replication of Nosema algerae (Microsporidia), a parasite of anopheline mosquitoes, in human cells above 36°C
The Journal of Eukaryotic Microbiology 46 (5), 464-468
Abstract: Microsporidia form a large and ubiquitous group of obligately intracellular parasitic eukaryotes, increasingly recognized as pathogens in humans. Transmission of invertebrate microsporidia to mammals has been considered impossible because temperature seemed to be a limiting factor for development. Nosema algerae, a microsporidian of anopheline mosquitoes, was cultured in human muscle fibroblasts at temperatures of 31° C and 38° C. This is the first record of an invertebrate microsporidian developing in human cells at a temperature above 36° C. The ultrastructure of N. algerue growing in human muscle fibroblasts is similar to that of Bruchiola vesicularum, a microsporidian species previously described in the muscle of an AIDS patient.
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Link to article at publishers website


Research topic(s) for pests/diseases/weeds:
biocontrol - natural enemies
Research topic(s) for beneficials or antagonists:
non-target effects/fate in environm.


Pest and/or beneficial records:

Beneficial Pest/Disease/Weed Crop/Product Country Quarant.


Anncaliia algerae (entomopathogen)