Plant Protection Science (2015) 51, 53-60

Ofir Degani (2015)
Cochliobolus heterostrophus T-toxin gene expression modulation via G protein and MAPK pathways
Plant Protection Science 51 (2), 53-60
Abstract: The role of G-protein and mitogen-activated protein kinase (MAPK) in filamentous fungi has been studied for over a decade, but downstream elements are less known. Here, we used microarray and Northern blot analysis to examine the involvement of these signalling pathways in controlling the known Cochliobolus heterostrophus T-toxin biosynthetic gene, DEC1, whose control is important in epidemic prevention. Comparison of the expression profile in wild-type strains and in G-protein and MAPK signalling deficient mutants revealed a unique, environmental-dependent control mechanism for the DEC1 gene. The results suggest, for the first time, a possible role in pathogenicity for the G-protein α2 subunit in this organism, and hint to a common role of G-protein α1 and β1 subunits and MAPK in maintaining accurate levels of this toxin during pathogenesis.
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Database assignments for author(s): Ofir Degani

Research topic(s) for pests/diseases/weeds:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Cochliobolus heterostrophus	Maize/corn (Zea mays)	Israel