Phytoparasitica (1997) 25, p. 92 (Gachechiladze et al.)

K.K. Gachechiladze, R.S. Adamia, N.S. Balardshishvili, T.G. Chanishvili and D.H. Krüger (1997)
Host-dependent modification/restriction and therapeutic potential of Pseudomonas phage
Phytoparasitica 25 (1), 92-92
The Xth International Congress of Virology, August 11-16, 1996, Jerusalem, Israel, lecture
Abstract: The recently isolated phages phi-ST3 and phi-ST1 were studied as to their lysis behavior and growth adaptation in ca 100 different P. aeruginosa strains. The replication of phi-ST3 varies greatly in the different host strains. A case of 'non-classical' modification and restriction was demonstrated which is caused by altered virus absorption to cells due to reversible virus protein modification by the former host strain. phi-ST1 displays stable lysis properties in most of the host strains. No case of non-classical (virus protein) or classical (virus DNA) modification/restriction was found. The latter can be explained by a selection against recognition sites of hosts' restriction enzymes in the viral genome. This makes phi-ST1 a candidate for therapeutic phage preparations.

Research topic(s) for pests/diseases/weeds:
biocontrol - natural enemies
Research topic(s) for beneficials or antagonists:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Pseudomonas aeruginosa (plant disease)
Pseudomonas phages (antagonist)	Pseudomonas aeruginosa (plant disease)