Pesticide Science (1998) 54, 27-34

G. Smagghe, T.S. Dhadialla, S. Derycke, L. Tirry and D. Degheele (1998)
Action of the ecdysteroid agonist tebufenozide in susceptible and artificially selected beet armyworm
Pesticide Science 54 (1), 27-34
Abstract: Toxicity assays with tebufenozide, the first commercial non-steroidal ecdysteroid agonist, against a laboratory strain of the beet armyworm, Spodoptera exigua (Hübner), demonstrated the promise of this new compound for the control of this important pest. Experiments to select insects artificially from the laboratory strain by continuous exposure of larval instars to corresponding LC₂₅ doses of tebufenozide for over 12 generations (G₀ -> G₁₂: 14-15 months), revealed no loss in susceptibility to the insecticide for up to five generations. Moreover, retention and fate of ¹⁴C-labelled tebufenozide were investigated using G₆ larvae from the selection experiments and the results compared with those for the susceptible (G₀) larvae. In addition, piperonyl butoxide, an inhibitor of monooxygenases, when ingested by larvae along with tebufenozide, increased the susceptibility of intoxicated larvae to this ecdysteroid agonist, indicating its oxidative metabolism in Spodoptera larvae.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Database assignments for author(s): Guy Smagghe, Luc Tirry

Research topic(s) for pests/diseases/weeds:
control - general

---

Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Spodoptera exigua