Mycopathologia (2008) 165, 51-59

Laetitia Pinson-Gadais, Florence Richard-Forget, Pierre Frasse, Christian Barreau, Bernard Cahagnier, Daniel Richard-Molard and Bénédicte Bakan (2008)
Magnesium represses trichothecene biosynthesis and modulates Tri5 , Tri6 , and Tri12 genes expression in Fusarium graminearum
Mycopathologia 165 (1), 51-59
Abstract: Growth and production of type-B trichothecenes mycotoxins by the Fusarium graminearum strain CBS 185.32 were compared in GYEP medium supplemented with Mg²⁺ at different concentrations (0-4 mM). Mg²⁺ led to a strong decrease in toxin accumulation without affecting the mycelial growth, suggesting a specific Mg²⁺ effect on fungal secondary metabolism. Expression of Tri5, Tri6, and Tri12 genes was followed throughout the time courses of type-B trichothecenes (TCTB) yield in standard and 2 mM Mg²⁺-supplemented GYEP media. Mg²⁺ addition significantly decreased Tri5, Tri6, and Tri12 expression. The inhibition of toxin production by Mg²⁺ was shown to be highly correlated with inhibition of Tri5 transcription and, to a lesser extend, of Tri6 and Tri12. This is the first report of a transcriptional control of TCTB production by Mg²⁺.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Christian Barreau

Research topic(s) for pests/diseases/weeds:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Fusarium graminearum