Molecular Plant-Microbe Interactions (2016) 29, 807-814

Tianhong Zhou, Chunyan Yin, Yingchao Zhang, Heng Shi, Jingru Wang, Linbo Sun, Xiaolong Shao, Ruxia Gao, Wei Wang and Xin Deng (2016)
Lon protease is involved in RhpRS-mediated regulation of type III secretion in Pseudomonas syringae
Molecular Plant-Microbe Interactions 29 (10), 807-814
Abstract: Pseudomonas syringae depends on the type III secretion system (T3SS) to directly translocate effectors into host cells. Previously, we reported a nonpathogenic rhpS mutant, suggesting that the two-component transduction system rhpRS is an important regulator of T3SS in P. syringae. rhpRS regulates itself and a variety of downstream genes under an inverted repeat element promoter in a phosphorylation-dependent manner. Here, we identify lon as a suppressor of the rhpS mutant through transposon screening. A lon/rhpS double mutant restored the phenotypes of the rhpS mutant. The expression level of lon was higher in rhpS and other T3SS-deficient mutants than the wild-type strain, suggesting a negative feedback mechanism between lon and T3SS genes. lon was also induced by a novel T3SS inhibitor, acetate, which substantially compromises the activation of T3SS genes in minimal medium and bacterial growth in host plants.
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Research topic(s) for pests/diseases/weeds:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Pseudomonas syringae