Journal of Virology (2013) 87, 11945-11949

Edwige Rancès, Travis K. Johnson, Jean Popovici, Iñaki Iturbe-Ormaetxe, Tasnim Zakir, Coral G. Warr and Scott L. O'Neill (2013)
The toll and imd pathways are not required for Wolbachia-mediated dengue virus interference
Journal of Virology 87 (21), 11945-11949
Abstract: Wolbachia blocks dengue virus replication in Drosophila melanogaster as well as in Aedes aegypti. Using the Drosophila model and mutations in the Toll and Imd pathways, we showed that neither pathway is required for expression of the dengue virus-blocking phenotype in the Drosophila host. This provides additional evidence that the mechanistic basis of Wolbachia-mediated dengue virus blocking in insects is more complex than simple priming of the host insect innate immune system.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Scott L. O'Neill

Research topic(s) for pests/diseases/weeds:
biocontrol - natural enemies
Research topic(s) for beneficials or antagonists:
general biology - morphology - evolution

---

Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Aedes aegypti
Wolbachia (genus - entomopathogens)	Aedes aegypti