Journal of Medical Entomology (2009) 46, 335-341

Julia W. Pridgeon, James J. Becnel, Gary G. Clark and Kenneth J. Linthicum (2009)
A high-throughput screening method to identify potential pesticides for mosquito control
Journal of Medical Entomology 46 (2), 335-341
Abstract: Mosquitoes that transmit human diseases are of major importance to the international public health community. Pesticides remain a major component of integrated programs to control these medically important species. However, very few types of pesticides are currently registered for mosquito control. A high-throughput screening method using first-instar larvae of Aedes aegypti was created and evaluated in our laboratory to quickly screen large numbers of chemicals for activity against mosquitoes. LC₅₀ values of a representative group of compounds were determined using this high-throughput screening method and compared with LD₅₀ values determined by topical application against female adults of Ae. aegypti. Our results show that this high-throughput screening method is suitable for screening large numbers of candidate chemicals quickly to identify effective compounds.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Julia W. Pridgeon, James J. Becnel, Gary G. Clark

Research topic(s) for pests/diseases/weeds:
control - general

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Aedes aegypti