Experimental and Applied Acarology (2000) 24, 645-659

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G. Das, S. Ghosh, M.H. Khan and J.K. Sharma (2000)
Immunization of cross-bred cattle against Hyalomma anatolicum anatolicum by purified antigens
Experimental and Applied Acarology 24 (8), 645-659
Abstract: Extracts prepared from unfed larvae of Hyalomma anatolicum anatolicum were purified by immunoaffinity chromatography using anti-gut IgG as ligand. Affinity purified antigen (Aff-GHLAg) was used to immunize cross-bred (Bos taurus × B. indicus) calves of 6-7 months of age. Immunized calves rejected 70.6% larvae, 54.5% nymphs and 61.9% adults. No significant changes in the engorged weight of females was observed; however, significant decrease in the engorgement weight of larvae and nymphs was recorded. There was a significant decrease in the emerging nymphs (p < 0.05) and adults (p < 0.01) of the tick stages fed on immunized animals. SDS-PAGE analysis revealed three antigenic proteins of 100, 59.4 and 37 kDa responsible for induction of resistance in the host.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Srikant Ghosh

Research topic(s) for pests/diseases/weeds:
resistance/tolerance/defence of host
control - general


Pest and/or beneficial records:

Beneficial Pest/Disease/Weed Crop/Product Country Quarant.


Hyalomma anatolicum