Canadian Journal of Botany - Revue Canadienne de Botanique (1995) 73, S495-S505

Kim E. Hammond-Kosack and Jonathan D.G. Jones (1995)
Plant disease resistance genes: unravelling how they work
Canadian Journal of Botany - Revue Canadienne de Botanique 73 (S1), S495-S505
Abstract: Resistance (R) genes confer on a plant the ability to defend itself following microbial attack. Each R gene exhibits an extreme specificity of action and is only effective against a microbe that has the corresponding functional avirulence (Avr) gene. This article reviews the strategies and experimental approaches deployed to understand the molecular events underlying the specificity of action of various tomato Cf resistance genes that results in incompatibility to the fungal pathogen Cladosporium fulvum. Topics covered include the clustering of Cf genes, the biology of Cf-dependent incompatibility, the map-based and transposon tagging approaches used to clone the Cf-2 and Cf-9 genes, respectively, identification by mutagenesis of other plant loci required for full Cf-9 mediated resistance, the expression of a functional Avr9 gene in planta and its lethal consequences to Cf-9 containing plants, the physiological and molecular host responses to C. fulvum and AVR elicitor challenges and some genetic approaches to ascertain the crucial components of the defense response.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Kim E. Hammond-Kosack, Jonathan D.G. Jones

Research topic(s) for pests/diseases/weeds:
molecular biology - genes
resistance/tolerance/defence of host

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Fulvia fulva	Tomato (Solanum lycopersicum)