Archives of Virology (2007) 152, 2107-2111

B.A. Young, G.L. Hein, R. French and D.C. Stenger (2007)
Substitution of conserved cysteine residues in Wheat streak mosaic virus HC-Pro abolishes virus transmission by the wheat curl mite
Archives of Virology 152 (11), 2107-2111
Abstract: Substitutions in the amino-proximal region of wheat streak mosaic virus (WSMV) HC-Pro were evaluated for effects on transmission by the wheat curl mite (Aceria tosichella Keifer). Alanine substitution at cysteine residues 16, 46 and 49 abolished vector transmission. Although alanine substitution at Cys₂₀ had no effect, substitution with arginine reduced vector transmission efficiency. Random substitutions at other positions (Lys₇ to Asn, Asn₁₉ to Ile, and Arg₄₅ to Lys) did not affect vector transmission. These results suggest that a zinc-finger-like motif (His₁₃-X2-Cys₁₆-X29-Cys₄₆-X2-Cys₄₉) in WSMV HC-Pro is essential for vector transmission.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Roy French

Research topic(s) for pests/diseases/weeds:
transmission/dispersal of plant diseases

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Aceria tosichella
	Wheat streak mosaic virus