Archives of Virology (2002) 147, 2301-2312

S. Yang and M. Ravelonandro (2002)
Molecular studies of the synergistic interactions between Plum pox virus HC-Pro protein and Potato virus X
Archives of Virology 147 (12), 2301-2312
Abstract: Helper component proteinase (HC-Pro) is a multifunctional viral protein involved in vection and movement of potyvirus; suppression of host post-transcriptional gene silencing reaction; and synergism of potyvirus with other viruses, notably potexvirus. When the HC-Pro of plum pox potyvirus (PPV) was transiently expressed in N. benthamiana and N. clevelandii plants via potato virus X (PVX) vector, a highly synergistic response of leaf necrosis or plant death, was observed in PVXHC-infected plants. However, when mutations were introduced into the highly conserved "PTK" and "KITC" motifs of HC-Pro, known for their involvement in protein/protein interaction during aphid-mediated transmission of potyvirus, the resulting change of amino acid residue from lysine (K) to glutamic acid (E) in the "KITC" motif had no obvious influence.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Michel Ravelonandro

Research topic(s) for pests/diseases/weeds:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Plum pox virus