Entomologia Generalis (2019) 39, 61-72

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Giovanni Benelli, Filippo Maggi, Angelo Canale and Heinz Mehlhorn (2019)
Lyme disease is on the rise – How about tick repellents? A global view
Entomologia Generalis 39 (2), 61-72
Abstract: Ticks are widely recognized as important vectors of a broad range of disease-causing agents. Recently, a noteworthy rise of Lyme disease cases has been reported, outlining the timely importance to develop novel and effective acaricides and repellents to reduce host-tick interactions. In this scenario, we provide a concise global view about the available tick repellent compounds, covering both commercially marketed products, with special reference to diethyltoluamide (DEET), ethyl butylacetylaminopropionate (IR3535), icaridin (saltidin) and p-menthane-3,8-diol, as well as promising compounds under investigation in these years. Among the most effective plant-borne repellents, we highlighted the noteworthy bioactivity of alpha-pinene, geraniol, citronellol, carvacrol, thymol, nepetalactone DHN 1 and DHN 2, nootkatone, valencene-13-ol, eugenol, phenylethyl alcohol and cinnamyl alcohol. In the final sections, major challenges to formulate products maintaining their tick repellent power over time are discussed.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Giovanni Benelli, Angelo Canale

Research topic(s) for pests/diseases/weeds:
control - general


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Beneficial Pest/Disease/Weed Crop/Product Country Quarant.


Ixodes ricinus
Ixodes scapularis
Ixodes persulcatus