Journal of Pest Science (2017) 90, 693-699

Giovanni Benelli, Roman Pavela, Angelo Canale, Marcello Nicoletti, Riccardo Petrelli, Loredana Cappellacci, Rossana Galassi and Filippo Maggi (2017)
Isofuranodiene and germacrone from Smyrnium olusatrum essential oil as acaricides and oviposition inhibitors against Tetranychus urticae: impact of chemical stabilization of isofuranodiene by interaction with silver triflate
Journal of Pest Science 90 (2), 693-699
Abstract: In this research, we isolated the sesquiterpenoids isofuranodiene and germacrone from the essential oil of Smyrnium olusatrum (Apiaceae), and evaluated their potential against Tetranychus urticae (Tetranychidae), an important agricultural pest, which attacks over two hundred species of plants. We evaluated both compounds for their acute and chronic toxicity via tarsal toxicity assays and oviposition inhibitory effects. Since isofuranodiene is a thermosensitive molecule undergoing Cope rearrangement giving the less active isomer curzerene, we achieved its chemical stabilization by interaction with a silver(I) ion (Ag triflate, AgCF₃SO₃), and the isofuranodiene adduct was tested for acaricidal activity and oviposition inhibitory potential. Results showed that isofuranodiene achieved the lowest LD₅₀ values, both in acute (15.8 µg cm^-2) and chronic toxicity assays (11.9 µg cm^-3). The three tested products also led to significant oviposition inhibition, with IC₅₀ of 4.1 (isofuranodiene), 17.8 (germacrone) and 19.3 µg cm^-3 (isofuranodiene + AgCF₃SO₃). Overall, the results from this study allowed us to candidate the oxygenated sesquiterpene isofuranodiene isolated from the S. olusatrum essential oil as novel molecule to develop effective acaricides. In addition, we pointed out the potential value of chemical stabilization by interaction with a silver(I) ion (Ag triflate, AgCF₃SO₃) for the production of mite oviposition inhibitors.
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Link to article at publishers website
Database assignments for author(s): Giovanni Benelli, Angelo Canale, Roman Pavela, Marcello Nicoletti

Research topic(s) for pests/diseases/weeds:
control - general

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Tetranychus urticae