FEMS Microbiology Letters (2010) 302, 151-158

Manuel Rodríguez-Sanz, María Antúnez-Lamas, Carlos Rojas, Emilia López-Solanilla, José M. Palacios, Pablo Rodríguez-Palenzuela and Luis Rey (2010)
The Tat pathway of plant pathogen Dickeya dadantii 3937 contributes to virulence and fitness
FEMS Microbiology Letters 302 (2), 151-158
Abstract: Protein secretion plays a very important role in the virulence of the bacterium Dickeya dadantii, the causative agent of soft rot disease, in a wide range of plant species. We studied the contribution of the twin-arginine translocation (Tat) protein system to the adaptation of D. dadantii 3937 to different growth conditions and to the interaction with the plant host. First, a list of 44 putative Tat substrates was obtained using bioinformatic programs taking advantage of the availability of the complete sequence of this bacterium. Second, a tatC mutant strain was constructed and analysed. The mutant displayed a pleiotropic phenotype, showing limited growth in an iron-depleted medium, higher sensitivity to copper, reduced motility on soft agar plates and attenuated virulence in witloof chicory leaves. Our results indicate the Tat system as an important determinant of the virulence and fitness of D. dadantii 3937. Potential Tat substrates related to the tatC mutant phenotype are discussed.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Luis Rey, Pablo Rodriguez-Palenzuela

Research topic(s) for pests/diseases/weeds:
molecular biology - genes

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Pest and/or beneficial records:

Beneficial	Pest/Disease/Weed	Crop/Product	Country	Quarant.
	Dickeya dadantii