New Phytologist (2020) 228, 1431-1439
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Can natural gene drives be part of future fungal pathogen control strategies in plants?
New Phytologist 228 (4), 1431-1439
Abstract: - Globally, fungal pathogens cause enormous crop losses and current control practices are not always effective, economical or environmentally sustainable. Tools enabling genetic management of wild pathogen populations could potentially solve many problems associated with plant diseases.
- A natural gene drive from a heterologous species can be used in the globally important cereal pathogen Fusarium graminearum to remove pathogenic traits from contained populations of the fungus. The gene drive element became fixed in a freely crossing population in only three generations.
- Repeat-induced point mutation (RIP), a natural genome defence mechanism in fungi that causes C to T mutations during meiosis in highly similar sequences, may be useful to recall the gene drive following release, should a failsafe mechanism be required.
- We propose that gene drive technology is a potential tool to control plant pathogens once its efficacy is demonstrated under natural settings.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
Link to article at publishers website
Database assignments for author(s): Gavin C. Hunter, Kemal Kazan
Research topic(s) for pests/diseases/weeds:
molecular biology - genes
Pest and/or beneficial records:
| Beneficial | Pest/Disease/Weed | Crop/Product | Country | Quarant. |
|---|---|---|---|---|
| Fusarium graminearum |
