Letters in Applied Microbiology (2001) 33, 76-81

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J.P. Park, S.W. Kim, H.J. Hwang and J.W. Yun (2001)
Optimization of submerged culture conditions for the mycelial growth and exo-biopolymer production by Cordyceps militaris
Letters in Applied Microbiology 33 (1), 76-81
Abstract: Aims: The objective of the present study was to determine the optimal culture conditions for exo-biopolymer production by Cordyceps militaris in shake flask culture.
Methods and Results: The optimal temperature and initial pH for both mycelial growth and exo-biopolymer production by Cordyceps militaris in shake flask culture were found to be 20°C and 6·0, respectively. Sucrose (40 g l-1) and corn steep powder (10 g l-1) were the most suitable carbon and nitrogen source for both mycelial growth and exo-biopolymer production.
Conclusions: Under optimal culture conditions, the maximum exo-biopolymer concentration in a 5-l jar fermenter indicated 10·3 g l-1, which was approximately three times higher than that in shake flask culture.
Significance and Impact of the Study: This process can have a significant impact on the industrial scale when sucrose and corn steep powder were used as carbon and nitrogen source.
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Link to article at publishers website


Research topic(s) for pests/diseases/weeds:
biocontrol - natural enemies
Research topic(s) for beneficials or antagonists:
rearing/culturing/mass production


Pest and/or beneficial records:

Beneficial Pest/Disease/Weed Crop/Product Country Quarant.


Cordyceps militaris (entomopathogen)