Entomological Science (2015) 18, 1-20

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Motoko Ikeda, Rina Hamajima and Michihiro Kobayashi (2015)
Baculoviruses: diversity, evolution and manipulation of insects
Entomological Science 18 (1), 1-20
Abstract: Baculoviruses, members of the family Baculoviridae, are large, enveloped viruses that contain a double-stranded circular DNA genome of 80–180 kbp, encoding 90–180 putative proteins. These viruses are exclusively pathogenic for arthropods, particularly insects, and have been developed, or are being developed, as environmentally sound pesticides and eukaryotic vectors for foreign protein expression, surface display, gene delivery for gene therapy, vaccine production and drug screening. The baculoviruses contain a set of approximately 30 core genes that are conserved among all baculovirus genomes sequenced to date. Individual baculoviruses also contain a number of lineage- or species-specific genes that have greatly impacted the diversification and evolution of baculoviruses. In this review, we first describe the general properties and biology of baculoviruses and then focus on the baculovirus genes and mechanisms involved in the replication, spread and survival of baculoviruses within the context of their diversity, evolution and insect manipulation.
(The abstract is excluded from the Creative Commons licence and has been copied with permission by the publisher.)
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Research topic(s) for pests/diseases/weeds:
biocontrol - natural enemies
Research topic(s) for beneficials or antagonists:
review


Pest and/or beneficial records:

Beneficial Pest/Disease/Weed Crop/Product Country Quarant.
Autographa californica nucleopolyhedrovirus (entomopathogen)
Lymantria dispar multiple nucleopolyhedrovirus (entomopathogen)