Bacillus thuringiensis Cyt1A-toxin (entomopathogen)

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Bacillus thuringiensis Cyt1A-toxin (entomopathogen)

During sporulation, Bacillus thuringiensis var. israelensis produces a parasporal body containing 4 proteins (Cry4a, Cry4b, Cry11a and Cyt1A) that in combination are highly toxic to mosquito larvae. Cyt1A is a 27 kDa protein that makes up about half of the parasporal body. It has low toxicity on its own, but is important for the synergism of the 4 toxins. It forms a hexagonal, bipyramidal crystal.