Autographa californica nucleopolyhedrovirus (entomopathogen)

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AcMNPV occlusion bodies (OB) - A) scanning EM (×20,000), the silhouette of virions is visible on emptied OBs (E); B) transmission electron microscopy (×50,000) of cross section of one OB with virions (V) and nucleocapsids (NC) (click on image to enlarge it)
Authors: Aurélien Chateigner, Annie Bézier, Carole Labrousse, Davy Jiolle, Valérie Barbe and Elisabeth A. Herniou
Source: Viruses (2015) vol. 7(7), p. 3627

Autographa californica nucleopolyhedrovirus (AcMNPV) (entomopathogen)

The virus is the type species of the genus Alphabaculovirus. For a baculovirus it has an unusually wide host range, infecting more than 100 species of Lepidoptera. Members of the family Noctuidae are most sensitive to the virus.

The virus forms protein crystals (occlusion bodies) in the nuclei of the infected cells, each encloses several virions. Each virion contains several rod-shaped nucleocapsids. AcMNPV has a circular dsDNA genome of ~134 kb which encodes 151 ORFs, including 37 core genes which are shared by all viruses in the family Baculoviridae.

Synonyms:
Spodoptera exempta multiple NPV
Anagrapha falcifera NPV
Galleria mellonella NPV